"PPARgamma agonists induce lipogenesis and adipocyte differentiation."
"In addition to cold and beta3-agonists, PPARgamma agonists can also induce beige cell differentiation in the mouse, which was shown to require PRDM16."
"Ligand activated PPARgamma induces adipocyte differentiation, inhibits the production of proinflammatory mediators, and suppresses aromatase activity."
"Interestingly, PPARgamma agonists are known to promote white adipose tissue differentiation and expansion in pre-adipocytes and stimulate lipogenesis 39, similar to what we now observed in HSC."
"These results suggest that PPARgamma agonists promote neuro-glial differentiation by modulating distinct stemness and differentiation gene expression profile in NSCs."
"Because PPARgamma cleavage strongly correlated with metabolic changes in TAMs and the cleavage of PPARgamma impairs its transcriptional activity, we sought to determine whether PPARgamma depletion would promote TAM differentiation and recapitulate the metabolic reprogramming observed in differentiating TAMs."
"Interestingly, PPARgamma has been reported to crosstalk with activin A : on the one hand, activin A treatment can inhibit PPARgamma expression in 3T3-L1 preadipocytes, leading to reduced adipocytes differentiation [XREF_BIBR]; on the other hand, PPARgamma activation by rosiglitazone can decrease follistatin (activin A antagonist) mRNA levels in rat intestinal epithelial cells, leading to the gain-of-function of activin A, which mediates the effects of TZDs on cell proliferation [XREF_BIBR]."
"PPARgamma Regulates Trophoblast Proliferation and Promotes Labyrinthine Trilineage Differentiation."
"Tributyltin, triphenyltin, and, to a lesser extent, dibutyltin, are PPARgamma ligands that can induce adipocyte differentiation ([XREF_BIBR] (review) and more recent primary literature [XREF_BIBR, XREF_BIBR - XREF_BIBR])."
"Our new findings show that activation of normal human B cells increases PPARgamma protein levels, and that PPARgamma activation increases cell differentiation."