"Furthermore, tau and arachidonic acid together activate PLC-γ1 ( Hwang et al., 1996 )."
"These observations suggest that the activation of PLC-γ1 by tau might be facilitated by an increase in arachidonic acid concentration, which occurs in cells upon activation of cPLA 2 ( Fig. 5 )."
"PLCgamma1 can be activated by receptor tyrosine kinases (i.e. : PDGFR, EGFR, FGFR, Trk), as well as non receptor protein kinases (Src, Syk, Tec) or phosphatidic acid, tau protein and its analogue."