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Statements


ARHGDIA activates ESR1. 3 / 3
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"Furthermore, RhoGDI1 could increase both ligand dependent and -independent ERalpha activity."

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"Su et al. 41,42 have reported that RhoGDI1 can increase transcriptional activity of Estrogen Receptor alpha (ERalpha) via a RhoGTPase dependent pathway that acts on estrogen receptor co-activators GRI[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"Likewise, El Marzouk et al. 43 found that RhoGDI1 could enhance ERalpha regulated transcription, but that this activity was due in part to direct binding of RhoGDI1 and ERalpha in the nucleus."
Catalytically active ARHGDIA activates ESR1. 1 / 1
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"Modified assertion"