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IndraLab

Statements

databases
phosphosite cbn pc11 biopax bel_lc signor biogrid tas lincs_drug hprd trrust | geneways tees isi trips rlimsp medscan sparser reach
reading

KRAS-G12V leads to the phosphorylation of RPS6KB1 on T444. 1 / 1
1 |
bel
"these data suggest that mutant ras maintains constitutive phosphorylation of p70 at Thr389 and Thr421/Ser424. Figure 4B demonstrates, in 1 of 3 separate experiments, that readdition of IL-6 to wild type-expressing cells at day +3 reinduces phosphorylation of p70 on Thr389 and Thr421/Ser424, but has no effect on phosphorylation of Ser411. isoform of rps6kb1 in uniprot has 23 additional N-terminal amino acids--DD"