IndraLab
Statements
sparser
"In fasting and dexamethasone-treated rats, therefore, insulin-induced JAK2 tyrosine phosphorylation decreases, and the JAK2 protein expression is differentially regulated such that the insulin-induced JAK2 association with SHP2 and STAT1 shows opposite interactions with the kinase."
reach
"In mice treated with ASO, insulin induced Akt and Foxo1 phosphorylation and leptin induced JAK2 and STAT3 tyrosine phosphorylation were not altered, indicating that the blunted insulin and leptin effects on food intake in mice treated with ASO are independent from these pathways (XREF_FIG)."