A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

IndraLab

Statements

databases
phosphosite cbn pc11 biopax bel_lc signor biogrid tas lincs_drug hprd trrust | geneways tees isi trips rlimsp medscan sparser reach
reading

MTOR decreases the amount of EIF4EBP1. 1 / 24
| 23 1
reach
"In the present study, in excellent agreement with the previous reports, metformin markedly activated AMPK and inactivated mTOR, thereby decreasing the levels of downstream effectors p-S6K1 and p-4EBP1 in MCF-7 and FSaII cells in vitro (XREF_FIG)."
Kinase-active MTOR decreases the amount of EIF4EBP1. 1 / 1
1 |
bel
"phosphorylation of mTOR represses, through an adaptor protein known as Raptor, 4EBP1, an inhibitor of EIF4E"