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"However, given that pY-β-PIX/FAK/paxillin in Src inhibitor-treated podocytes was blunted basally but remained partially responsive to EGF stimulation, it is likely that Src is not the sole regulator of the signaling pathway responsible for EGF-mediated tyrosine phosphorylation of β-PIX, FAK, and paxillin.Collectively, our findings support a model wherein CdGAP interacts with β-PIX in the cytoplasm and contributes to maintaining low Rac1/Cdc42 activity at basal conditions."