A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

IndraLab

Statements

databases
phosphosite cbn pc11 biopax bel_lc signor biogrid tas lincs_drug hprd trrust | geneways tees isi trips rlimsp medscan sparser reach
reading

EGF increases the amount of CCND1. 4 / 14
2 | 5
bel
"DHT and EGF up-regulated cyclinD1 (CD1) at both mRNA and protein levels in A549 cells"
bel
"Levels of cyclin D1 protein were elevated following 3 h arsenic and EGF (Fig. 2A, row 1 CCND1). The positive control, EGF also induced a large increase in cyclin D1 levels."
reach
"In line with this finding, reconstituted expression of rCdc25A Y59F mutant inhibited EGF enhanced mRNA (XREF_SUPPLEMENTARY) and protein expression (XREF_FIG) of CCND1 and MYC and c-Myc-upregulated GLUT1, PKM2 and LDHA."
reach
"This reflected the observed EGF induced increase in CCND1 mRNA expression (XREF_FIG), occurring irrespective of TIMP1 expression (XREF_FIG) as a confirmation of its separation from invasion signalling."
Transcriptionally active EGF increases the amount of CCND1. 3 / 3
3 |
biopax:ctd
No evidence text available
biopax:ctd
No evidence text available
biopax:ctd
No evidence text available