A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

IndraLab

Statements

databases
phosphosite cbn pc11 biopax bel_lc signor biogrid tas lincs_drug hprd trrust | geneways tees isi trips rlimsp medscan sparser reach
reading

Catalytically active AGER increases the amount of SERPINE1. 2 / 2
2 |
bel
"Furthermore, we have previously shown that AGEs inhibited prostacyclin production and induced PAI-1 generation in endothelial cells through an interaction with RAGE (Yamagishi et al., 1998; Yamagishi et al., 1996)."
bel
"RAGE antibody prevented glyLDL-induced up-regulation of PAI-1 in EC (P < 0.05) (Fig. 1B)."
AGER increases the amount of SERPINE1. 1 / 1
| 1
reach
"Gly LDL actives RAGE and a cascade including H-Ras, Raf-1, NOX, ROS, and HSF-1, and consequently increases the expression of PAI-1 XREF_BIBR - XREF_BIBR."