Other Services

This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

CXCR4 increases the amount of AKT. 2 / 3

1 | 1

➶

bel

"Treatment of LN827 cells with SDF-1alpha showed prolonged activation of survival kinase, Akt through its receptor CXCR4."

12388552

➶

reach

"Evidence also demonstrated that CXCR4 markedly upregulated the expression levels of PI3K and Akt."

34584545

Modified CXCR4 increases the amount of phosphorylated AKT. 1 / 1

| 1

➶

reach

"Overexpression of CXCR4 activated cyclin D1 and p-Akt expression, but inhibited p21 expression."

25145299

Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...