IndraLab

Statements

TNF decreases the amount of CASP3. 10 / 11
1 | 9
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"The expression of apoptosis-inducing proteases ICH-1L and CPP32 was reduced by treatment of the synovial cells with TNF-alpha."
9764613
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"The potential mechanism could be that PF decreased and inhibited BNP, TNF-alpha and IL-6, increased IL-10 and further inhibited the expression of Caspase-3 and Caspase-9, thus promoting ventricular remodeling."
29695894
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"As shown in XREF_FIG, TNF-alpha markedly (p < 0.05) increased protein levels of both caspase-3 and p17 and cleaved PARP, and decreased protein levels of pro-caspase-3 and PARP."
27847386
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"The relative expression of TNF-α, 8-OHDG, and caspase-3 genes of each HepG2 and MCF-7 cell line using ELISA assays demonstrated that ADFL, UFS, and GFS samples reduced the expression of TNF-α and 8-OHDG genes but increased the expression of the caspase-3 gene."
36826005
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"In addition, beetroot extract also reduced the generation of RSOS, TNF-α, and IL-6, inhibited NF-κB, enhanced catalase and Bcl2, and reduced the levels of Bax and cleaved caspase-3 in the kidneys of gentamicin-treated rats [61]."
| PMC
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"Administration of TNF-alpha significantly downregulated the expression of GFAP, ICAM-1, and caspase-3 in the brain tissue compared with that in the I/R group (P < 0.05)."
28356740
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"According to some studies, inducing necrosis and apoptosis or reactivating TB, especially in immunocompromised patients, can lead to an increase in interleukin (IL)-17 and tumor necrosis factor (TNF)-α, which can either decrease tumor protein 53 (TP53) activity or increase B-cell lymphoma 2 (Bcl-2) expression, decrease (Bcl-2-associated X protein) Bax expression, and inhibit caspase-3 expression by reducing mitochondrial cytochrome oxidase expression [40,41]."
34361097
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"Moreover, inhibition of HIF1A-AS1 markedly reduced mRNA level of caspase 3 which can be significantly enhanced by TNF-alpha."
29369172
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"Invitro, TNF-alpha did not affect cumulus cells expansion, but reduced the HAS2, CASP3 and CASP6 mRNA levels in cumulus cells after 12h."
28166953
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"TNF-alpha antibody treatment significantly suppressed mRNA expression of TNF-alpha, caspase-3 and caspase-8."
25130514