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IndraLab

Statements

databases
phosphosite cbn pc11 biopax bel_lc signor biogrid tas lincs_drug hprd trrust | geneways tees isi trips rlimsp medscan sparser reach
reading

Kinase-active TGFBR2 increases the amount of SMAD2 bound to SMAD3 and SMAD4. 1 / 1
1 |
bel
"a dimeric Smac/DIABLO molecule is required for binding to BIR2, but not to BIR3, which indicates significant differences in the affinity or mechanism by which Smac/DIABLO binds to these domains Figure 5: Association of IAPs with signalling complexes."
TGFBR2 increases the amount of SMAD2. 1 / 1
| 1
reach
"Noteworthy, the SP cells sustain Bmpr1a (Alk3) and Bmpr2 (BMPRII) expression, and upregulate Alk5 (Tgfbr1) and TbetaRII (Tgfbr2), which lead to increased levels of pSmad2."