A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.



phosphosite cbn pc11 biopax bel_lc signor biogrid tas lincs_drug hprd trrust | geneways tees isi trips rlimsp medscan sparser reach

Kinase-active TGFBR2 increases the amount of SMAD2 bound to SMAD3 and SMAD4. 1 / 1
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"a dimeric Smac/DIABLO molecule is required for binding to BIR2, but not to BIR3, which indicates significant differences in the affinity or mechanism by which Smac/DIABLO binds to these domains Figure 5: Association of IAPs with signalling complexes."
TGFBR2 increases the amount of SMAD2. 1 / 1
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"Noteworthy, the SP cells sustain Bmpr1a (Alk3) and Bmpr2 (BMPRII) expression, and upregulate Alk5 (Tgfbr1) and TbetaRII (Tgfbr2), which lead to increased levels of pSmad2."