A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

IndraLab

Statements

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phosphosite cbn pc11 biopax bel_lc signor biogrid tas lincs_drug hprd trrust | geneways tees isi trips rlimsp medscan sparser reach
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"Previous EoE studies have shown that TGF-beta1 plays a role in esophageal remodeling, participates in esophageal smooth muscle contraction, stimulates fibroblast secretion of extracellular matrix, and contributes to esophageal epithelial to mesenchymal transition (EMT) XREF_BIBR, XREF_BIBR, XREF_BIBR - XREF_BIBR."
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"TGF-beta1 induced epithelial to mesenchymal transition (EMT) in alveolar epithelial cells and could contribute to enhance fibrosis in idiopathic lung fibrosis."
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"Exogenous angiotensin (1-7) directly inhibits epithelial-mesenchymal transformation induced by transforming growth factor-beta1 in alveolar epithelial cells."
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"The current research was designed to study the role of hydrogen in renal fibrosis and the renal epithelial to mesenchymal transition (EMT) induced by transforming growth factor-beta1 (TGF-beta1)."
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"Epithelial to mesenchymal transition (EMT) is induced by transforming growth factor-beta1 (TGF-beta1) and is a crucial event for cancer cells to acquire invasive and metastatic phenotypes."
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"The related kinase JNK1 contributes to TGFbeta1 induced epithelial to mesenchymal transition and collagen deposition, and has been shown to be necessary for the development of pulmonary fibrosis in a mouse model XREF_BIBR; however contrary to our findings, this study reports that JNK3 expression is limited to heart, testis, and brain."
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"To understand the non canonical mechanisms of p21 regulation in CRC, in Bauer et al. 16, we observed that at later time points, both Activin A and TGFbeta1 induce migration and epithelial to mesenchymal transition (EMT) in a SMAD4 independent manner (XREF_FIG)."
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"Laminin-5 with transforming growth factor-beta1 induces epithelial to mesenchymal transition in hepatocellular carcinoma."
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"TGF beta1 triggers epithelial-mesenchymal transformation of RPE cells into RPE fibrous metaplasia."
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"Taken together, our study here revealed that thyroid hormone T3 could inhibit TGFbeta1 induced renal tubular epithelial to mesenchymal transition by increasing miR34a expression."
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"It was demonstrated that expression of miR-20a is induced by increased levels of TGF-beta1 in GBC that leads to epithelial to mesenchymal transition (EMT) mediated through inhibition of Smad7 transcription and activation of beta-catenin signaling pathway [XREF_BIBR]."