IndraLab

Statements

TGFB1 phosphorylates SRC. 10 / 16
1 | 6 8
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"The present study demonstrates for the first time that activation of Smad signaling is partly dependent on non-ligand–mediated EGFR transactivation induced by TGF-β1–induced Src phosphorylation."
28943431
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"Here, we showed that TGF-beta1 strongly induced the phosphorylation of FAK, Src, and paxillin, while KY-05009 inhibited these inductions."
25337707
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"We show that TGF-beta1 activates the epidermal growth factor receptor (EGFR) and phosphorylates c-Src."
15856020
bel
"We show that TGF-beta1 activates the epidermal growth factor receptor (EGFR) and phosphorylates c-Src."
15856020
sparser
"CSE-mediated TGF-β1 activates the phosphorylation of FAK, Syk and Src to induce EMT processes in RPE cells."
29286114
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"TGF-beta1 has been reported to activate EGF signaling in hepatocytes by promoting the shedding of EGF like ligands and phosphorylation of Src."
23334091
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"CSE mediated TGF-beta1 activates the phosphorylation of FAK, Syk and Src to induce EMT processes in RPE cells."
29286114
sparser
"Furthermore, TGF-β1-initiated Src phosphorylation of caveolin-1 Y14 is critical in Rho-ROCK-mediated suppression of the SMAD phosphatase PPM1A maintaining and, accordingly, SMAD2/3-dependent transcription of the PAI-1 gene."
31382626
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"Similarly, PP1 dose-dependently inhibited TGF-β1–induced Src phosphorylation (Tyr416), whereas total Src expression was not affected by this agent ( xref )."
26444028
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"Similarly with these results, the TGF-β1-induced phosphorylation of FAK and Src, and expression of α-smooth muscle action (SMA) were strongly inhibited in human normal lung fibroblast CCD-18Lu by CX-4945 ( xref )."
24023938
TGFB1 leads to the phosphorylation of SRC on Y419. 4 / 4
| 3 1
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"TGF-beta1 stimulation of quiescent VSMC results in phosphorylation (at Y416) of the non receptor tyrosine kinase pp60 c- src and the rapid activation of the epidermal growth factor receptor (EGFR) atY845 (a src-target residue)."
19132220
sparser
"VSMC pretreatment with the src kinase-specific inhibitor SU6656, as expected, prevented the TGF-β1-dependent increase in c- Src Y416 phosphorylation ( xref )."
21829547
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"As shown in XREF_FIG, TGF-beta1 induced the phosphorylation of FAK (Y925), Src (Y416), and paxillin (Y118), and these phosphorylation events were inhibited by KY-05009."
25337707
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"Both hypotonicity and TGF beta1 treatment increased phosphorylation of Src Tyr416 but did not effect Src kinase expression."
26877779
TGFB1 leads to the phosphorylation of SRC on tyrosine. 1 / 1
| 1
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"TGF-beta1 stimulation of quiescent VSMC results in phosphorylation (at Y416) of the non receptor tyrosine kinase pp60 c- src and the rapid activation of the epidermal growth factor receptor (EGFR) atY845 (a src-target residue)."
19132220