IndraLab

Statements

SRC increases the amount of IGF1R. 6 / 6
| 6
reach
"Furthermore, AKT induced IGF-IR expression was down-regulated by dominant negative Src or PTEN."
11212254
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"Active Src can also activate Akt, and both Src and Akt up-regulate IGF-1R expression in this cancer."
21422497
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"Inhibition of Src and Akt signaling failed to block the increase in IGF-1R expression, ruling out these pathways as the mechanism for IGF-1R induction in chemoresistant cell lines."
19244128
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"Active Src can also activate Akt, and both Src and Akt up-regulate IGF-1R expression in this cancer."
23006971
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"It has been postulated that c-Src may induce transformation by causing the overexpression of the insulinlike growth factor-1 receptor (IGF-1R) in pancreatic tumor cell lines."
14627343
reach
"Inhibition of the Src and MAPK pathway decreases IGF-1R expression and decreases ERK1/2 phosphorylation."
26816736
Kinase-active SRC increases the amount of IGF1R. 1 / 1
1 |
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"Modified assertion"
11212254