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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

Modified RPS6KB1 increases the amount of RPS6. 1 / 1

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"Overexpression of WT S6K1 or S6K1-CA mutant significantly increased pS6 levels, whereas S6K1-DN decreased them."

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RPS6KB1 increases the amount of RPS6. 1 / 1

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"Next we confirmed that S6K1-CA injection significantly increased pS6 levels in SOCS3 KO mice (XREF_SUPPLEMENTARY)."

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Kinase-active RPS6KB1 increases the amount of RPS6. 1 / 1

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"IFNgamma-activated p70 S6 kinase subsequently phosphorylates the 40S S6 ribosomal protein on serines 235/236, to regulate IFNgamma-dependent mRNA translation."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...