IndraLab

Statements

USP35 affects TNIP2
1 | 5
USP35 deubiquitinates TNIP2. 5 / 5
1 | 4
reach
"These data illustrated that USP35 could promote ABIN-2 deubiquitination and decrease its proteasomal degradation."
26348204
reach
"USP35 deubiquitinates and stabilizes ABIN-2 protein."
26348204
ubibrowser
"Collectively, our data indicated that miR let-7a-regulated USP35 can inhibit NF-kappaB activation by deubiquitination and stabilization of ABIN-2 protein and eventually inhibit cell proliferation."
26348204
reach
"Together, these data illustrated that USP35 could up-regulate the expression of ABIN-2 by promoting ABIN-2 deubiquitination and decreasing its proteasomal degradation."
26348204
reach
"Subsequently, we presented a serial evidence to show that USP35 could deubiquitinate and stabilize ABIN-2 in cancer cells."
26348204
Modified USP35 leads to the deubiquitination of TNIP2. 1 / 1
| 1
reach
"Immunoprecipitation with Flag-ABIN-2 followed by HA-Ub immunoblotting showed overexpression of USP35 dramatically decreased the ABIN-2 ubiquitination."
26348204
USP35 affects VDAC1
1 |
USP35 deubiquitinates VDAC1. 1 / 1
1 |
USP35 affects STING1
| 1
USP35 deubiquitinates STING1. 1 / 1
| 1
reach
"Our data further showed that USP35 can directly deubiquitinate and inactivate STING."
32678307
USP35 affects PRKN
| 1
USP35 deubiquitinates PRKN. 1 / 1
| 1
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"Reciprocally, the dequbiquitination enzymes USP30 and USP35 have been shown to antagonize the mitophagy process by deubiquitinating Parkin [138,139]."
30544615
USP35 affects ESR1
| 1
USP35 leads to the deubiquitination of ESR1. 1 / 1
| 1
reach
"Mechanistically, USP35 enhanced ERalpha stability by interacting and deubiquitinating ERalpha, and transcriptional activity of ERalpha by interacting with ERalpha in DNA regions containing estrogen response element."
34131114
USP35 affects BRPF1
| 1
USP35 deubiquitinates BRPF1. 1 / 1
| 1
reach
"Mechanistically, we found that USP35 could directly deubiquitinate and stabilize BRPF1 proteins."
36357379
USP35 affects BIRC5
| 1
USP35 leads to the deubiquitination of BIRC5. 1 / 1
| 1
reach
"USP35 interacted with and promoted the deubiquitination of the survivin protein."
34438346
USP35 affects AURKB
1 |
USP35 deubiquitinates AURKB. 1 / 1
1 |
ubibrowser
"Recently, we have found that USP35 acts as a deubiquitinating enzyme (DUB) for Aurora B and affects its stability during cell division, thus being involved in the regulation of mitosis."
29764563