IndraLab

Statements


EIF3H deubiquitinates SNAI1. 3 / 3
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"We observed overexpression of EIF3H deubiquitinated endogenous Snail, but knockdown of EIF3H facilitated ubiquitination of endogenous Snail."

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"Furthermore, we demonstrated Snail, as the novel identified substrate of EIF3H, could be deubiquitinated and stabilized by EIF3H."

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"EIF3H interacts with and deubiquitinates Snail to prolong its half-life."
Modified EIF3H leads to the deubiquitination of SNAI1. 1 / 1
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"When co-expressed Snail-Flag with EIF3H in HEK293T cells, we found that Snail ubiquitination could be abolished by EIF3H overexpression."