IndraLab

Statements


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Valproic acid increases the amount of MINDY2.
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Valproic acid increases the amount of MINDY2. 2 / 2
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No evidence text available

No evidence text available
Valproic acid decreases the amount of MINDY2.
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Valproic acid decreases the amount of MINDY2. 1 / 1
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No evidence text available
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Pirinixic acid decreases the amount of MINDY2.
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Pirinixic acid decreases the amount of MINDY2. 2 / 2
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No evidence text available

No evidence text available
Pirinixic acid activates MINDY2.
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No evidence text available
MINDY2 is modified
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MINDY2 is phosphorylated on S94. 3 / 3
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No evidence text available

No evidence text available

No evidence text available

eidos
"The deubiquitinating enzyme MINDY2 promotes pancreatic cancer proliferation and metastasis by stabilizing ACTN4 expression and activating the PI3K / AKT / mTOR signaling pathway ."

reach
"In vivo and in vitro experiments further suggested that elevated MINDY2 promotes PC proliferation, invasive metastasis, and EMT."

eidos
"In vivo and in vitro experiments further suggested that elevated MINDY2 promotes PC proliferation , invasive metastasis , and EMT ."
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Carbon nanotube decreases the amount of MINDY2. 2 / 2
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No evidence text available

No evidence text available
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Bisphenol A increases the amount of MINDY2.
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Bisphenol A increases the amount of MINDY2. 1 / 1
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No evidence text available
Bisphenol A decreases the amount of MINDY2.
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Bisphenol A decreases the amount of MINDY2. 1 / 1
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No evidence text available
XXYLT1 affects MINDY2
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No evidence text available

No evidence text available
USP22 affects MINDY2
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No evidence text available

No evidence text available
SLC2A8 affects MINDY2
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No evidence text available

No evidence text available
SLC27A2 affects MINDY2
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No evidence text available

No evidence text available
SCCPDH affects MINDY2
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No evidence text available

No evidence text available
RETSAT affects MINDY2
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No evidence text available

No evidence text available
PTRH2 affects MINDY2
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No evidence text available

No evidence text available
PRAF2 affects MINDY2
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No evidence text available

No evidence text available
PPM1B affects MINDY2
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No evidence text available

No evidence text available

reach
"In vivo and in vitro experiments further suggested that elevated MINDY2 promotes PC proliferation, invasive metastasis, and EMT."

eidos
"In vivo and in vitro experiments further suggested that elevated MINDY2 promotes PC proliferation , invasive metastasis , and EMT ."
MINDY2 affects XXYLT1
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No evidence text available

No evidence text available
MINDY2 affects USP22
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No evidence text available

No evidence text available
MINDY2 affects SLC2A8
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No evidence text available

No evidence text available
MINDY2 affects SLC27A2
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No evidence text available

No evidence text available
MINDY2 affects SCCPDH
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No evidence text available

No evidence text available
MINDY2 affects RETSAT
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No evidence text available

No evidence text available
MINDY2 affects PTRH2
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No evidence text available

No evidence text available
MINDY2 affects PRAF2
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No evidence text available

No evidence text available
MINDY2 affects PPM1B
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No evidence text available

No evidence text available
| 1 1

reach
"In vivo and in vitro experiments further suggested that elevated MINDY2 promotes PC proliferation, invasive metastasis, and EMT."

eidos
"The deubiquitinating enzyme MINDY2 promotes pancreatic cancer proliferation and metastasis by stabilizing ACTN4 expression and activating the PI3K / AKT / mTOR signaling pathway ."
MINDY2 affects MBLAC2
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No evidence text available

No evidence text available
MINDY2 affects KCNJ11
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No evidence text available

No evidence text available
MINDY2 affects GNPAT
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No evidence text available

No evidence text available
MINDY2 affects DNAJC1
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No evidence text available

No evidence text available
MINDY2 affects CYP2J2
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No evidence text available

No evidence text available
MINDY2 affects ARL8B
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No evidence text available

No evidence text available
MINDY2 affects ARL13B
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No evidence text available

No evidence text available
MBLAC2 affects MINDY2
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No evidence text available

No evidence text available
KCNJ11 affects MINDY2
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No evidence text available

No evidence text available
GNPAT affects MINDY2
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No evidence text available

No evidence text available
DNAJC1 affects MINDY2
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No evidence text available

No evidence text available
CYP2J2 affects MINDY2
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No evidence text available

No evidence text available
ARL8B affects MINDY2
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No evidence text available

No evidence text available
ARL13B affects MINDY2
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No evidence text available

No evidence text available
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Troglitazone decreases the amount of MINDY2. 1 / 1
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No evidence text available
Succimer affects MINDY2
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Succimer decreases the amount of MINDY2. 1 / 1
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No evidence text available
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Sodium arsenite decreases the amount of MINDY2. 1 / 1
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No evidence text available
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Sodium arsenate increases the amount of MINDY2. 1 / 1
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No evidence text available
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Propiconazole decreases the amount of MINDY2. 1 / 1
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No evidence text available
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Phenobarbital decreases the amount of MINDY2. 1 / 1
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No evidence text available
Miconazole affects MINDY2
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Miconazole decreases the amount of MINDY2. 1 / 1
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No evidence text available
Methylmercury chloride decreases the amount of MINDY2. 1 / 1
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No evidence text available
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Methamphetamine increases the amount of MINDY2. 1 / 1
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No evidence text available
Magnetite nanoparticle decreases the amount of MINDY2. 1 / 1
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No evidence text available
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Hydroperoxide decreases the amount of MINDY2. 1 / 1
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No evidence text available
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Hsa-miR-769-3p decreases the amount of MINDY2. 1 / 1
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No evidence text available
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Hsa-miR-7151-3p decreases the amount of MINDY2. 1 / 1
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No evidence text available
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Hsa-miR-7-5p decreases the amount of MINDY2. 1 / 1
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No evidence text available
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Hsa-miR-6851-3p decreases the amount of MINDY2. 1 / 1
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No evidence text available
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Hsa-miR-6832-5p decreases the amount of MINDY2. 1 / 1
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No evidence text available
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Hsa-miR-6823-5p decreases the amount of MINDY2. 1 / 1
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No evidence text available
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Hsa-miR-6759-3p decreases the amount of MINDY2. 1 / 1
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No evidence text available
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Hsa-miR-6728-5p decreases the amount of MINDY2. 1 / 1
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No evidence text available
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Hsa-miR-6513-5p decreases the amount of MINDY2. 1 / 1
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No evidence text available
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Hsa-miR-6504-3p decreases the amount of MINDY2. 1 / 1
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No evidence text available
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Hsa-miR-619-5p decreases the amount of MINDY2. 1 / 1
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No evidence text available
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Hsa-miR-6077 decreases the amount of MINDY2. 1 / 1
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No evidence text available
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Hsa-miR-5580-5p decreases the amount of MINDY2. 1 / 1
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No evidence text available
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Hsa-miR-5100 decreases the amount of MINDY2. 1 / 1
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No evidence text available
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Hsa-miR-510-3p decreases the amount of MINDY2. 1 / 1
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No evidence text available
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Hsa-miR-5096 decreases the amount of MINDY2. 1 / 1
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No evidence text available
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Hsa-miR-5095 decreases the amount of MINDY2. 1 / 1
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No evidence text available
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Hsa-miR-5089-5p decreases the amount of MINDY2. 1 / 1
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No evidence text available
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Hsa-miR-494-3p decreases the amount of MINDY2. 1 / 1
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No evidence text available
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Hsa-miR-4802-3p decreases the amount of MINDY2. 1 / 1
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No evidence text available
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Hsa-miR-4781-3p decreases the amount of MINDY2. 1 / 1
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No evidence text available
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Hsa-miR-4755-3p decreases the amount of MINDY2. 1 / 1
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No evidence text available
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Hsa-miR-4670-3p decreases the amount of MINDY2. 1 / 1
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No evidence text available
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Hsa-miR-4524b-3p decreases the amount of MINDY2. 1 / 1
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No evidence text available
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Hsa-miR-4524a-3p decreases the amount of MINDY2. 1 / 1
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No evidence text available
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Hsa-miR-450b-3p decreases the amount of MINDY2. 1 / 1
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No evidence text available
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Hsa-miR-4438 decreases the amount of MINDY2. 1 / 1
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No evidence text available
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Hsa-miR-4435 decreases the amount of MINDY2. 1 / 1
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No evidence text available
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Hsa-miR-4425 decreases the amount of MINDY2. 1 / 1
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No evidence text available
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Hsa-miR-4252 decreases the amount of MINDY2. 1 / 1
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No evidence text available
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Hsa-miR-411-5p decreases the amount of MINDY2. 1 / 1
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No evidence text available
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Hsa-miR-409-3p decreases the amount of MINDY2. 1 / 1
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No evidence text available
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Hsa-miR-3942-3p decreases the amount of MINDY2. 1 / 1
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No evidence text available
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Hsa-miR-375 decreases the amount of MINDY2. 1 / 1
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No evidence text available
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Hsa-miR-335-5p decreases the amount of MINDY2. 1 / 1
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No evidence text available
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Hsa-miR-3190-5p decreases the amount of MINDY2. 1 / 1
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No evidence text available
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Hsa-miR-3185 decreases the amount of MINDY2. 1 / 1
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No evidence text available
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Hsa-miR-3147 decreases the amount of MINDY2. 1 / 1
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No evidence text available
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Hsa-miR-197-3p decreases the amount of MINDY2. 1 / 1
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No evidence text available
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Hsa-miR-192-5p decreases the amount of MINDY2. 1 / 1
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No evidence text available
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Hsa-miR-1273g-3p decreases the amount of MINDY2. 1 / 1
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No evidence text available
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Hsa-miR-124-3p decreases the amount of MINDY2. 1 / 1
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No evidence text available
Flutamide affects MINDY2
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Flutamide decreases the amount of MINDY2. 1 / 1
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No evidence text available
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Doxorubicin decreases the amount of MINDY2. 1 / 1
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No evidence text available
Diuron affects MINDY2
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Diuron increases the amount of MINDY2. 1 / 1
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No evidence text available
Clofibrate affects MINDY2
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Clofibrate decreases the amount of MINDY2. 1 / 1
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No evidence text available
Cisplatin affects MINDY2
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Cisplatin decreases the amount of MINDY2. 1 / 1
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No evidence text available
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Chlorpyrifos decreases the amount of MINDY2. 1 / 1
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No evidence text available
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Chloroprene increases the amount of MINDY2. 1 / 1
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No evidence text available
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Aflatoxin B1 increases the amount of MINDY2. 1 / 1
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No evidence text available
TLX2 affects MINDY2
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TLX2 decreases the amount of MINDY2. 1 / 1
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No evidence text available
Soman affects MINDY2
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Soman decreases the amount of MINDY2. 1 / 1
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No evidence text available
SREBF1 affects MINDY2
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SREBF1 decreases the amount of MINDY2. 1 / 1
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No evidence text available
SLC27A6 affects MINDY2
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No evidence text available

No evidence text available
RUNX2 affects MINDY2
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RUNX2 decreases the amount of MINDY2. 1 / 1
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No evidence text available
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Plant Extracts increases the amount of MINDY2. 1 / 1
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No evidence text available
NF1 affects MINDY2
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NF1 decreases the amount of MINDY2. 1 / 1
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No evidence text available
NCR3LG1 affects MINDY2
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No evidence text available
Mutating key residues site MINDY2 affects MINDY2
| 1
Mutating key residues site MINDY2 inhibits MINDY2. 1 / 1
| 1

eidos
"Mutating key residues at each site on MINDY2 to weaken the interaction with Ub impedes the ability of MINDY2 to cleave pentaUb ( Figures 5F , 5H , 5J , and 5K ) ."

reach
"Bioinformatics Analysis and Western blot experiments further confirmed that MINDY2 stabilizes ACTN4 through deubiquitination and thus activates the PI3K/AKT/mTOR signaling pathway."
MINDY2 affects fluorescent cleavage products
| 1
MINDY2 activates fluorescent cleavage products. 1 / 1
| 1

eidos
"However , we observe that both MINDY1 and MINDY2 rapidly produce a range of fluorescent cleavage products that lie between Ub1 and Ub7 , suggesting endo-activity as the DUB can cleave anywhere within the polyUb chain , resulting in the formation of chains of all intermediate lengths as products ( Figures 6C and 6D ) ."

reach
"In vivo and in vitro experiments further suggested that elevated MINDY2 promotes PC proliferation, invasive metastasis, and EMT."
MINDY2 affects SLC27A6
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No evidence text available
MINDY2 affects PI3K/AKT/mTOR
| 1
MINDY2 activates PI3K/AKT/mTOR. 1 / 1
| 1

reach
"Bioinformatics Analysis and Western blot experiments further confirmed that MINDY2 stabilizes ACTN4 through deubiquitination and thus activates the PI3K/AKT/mTOR signaling pathway."
MINDY2 affects NCR3LG1
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No evidence text available
MINDY2 affects MINDY2
| 1
MINDY2 leads to the methylation of MINDY2. 1 / 1
| 1

reach
"Overall, this suggests that the FAM63B methylation differences seen in whole blood from BD and controls are not strongly driven by SNPs in FAM63B, at least those that are on the Affymetrix 500K array."
MINDY2 affects KLC1
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No evidence text available
MINDY2 affects IKBIP
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No evidence text available
MINDY2 affects HSDL1
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No evidence text available
MINDY2 affects GNA13
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No evidence text available
MINDY2 affects CTU1
1 |
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No evidence text available
MINDY2 affects ALG11
1 |
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No evidence text available
MINDY2 affects ACTN4
| 1
MINDY2 increases the amount of ACTN4. 1 / 1
| 1

reach
"The deubiquitinating enzyme MINDY2 promotes pancreatic cancer proliferation and metastasis by stabilizing ACTN4 expression and activating the PI3K/AKT/mTOR signaling pathway."
MEF2A affects MINDY2
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MEF2A decreases the amount of MINDY2. 1 / 1
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No evidence text available
KLC1 affects MINDY2
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No evidence text available
IKBIP affects MINDY2
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No evidence text available
HSDL1 affects MINDY2
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No evidence text available
GNA13 affects MINDY2
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No evidence text available
ELK1 affects MINDY2
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ELK1 decreases the amount of MINDY2. 1 / 1
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No evidence text available
CTU1 affects MINDY2
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No evidence text available
ALG11 affects MINDY2
1 |
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No evidence text available