IndraLab

Statements


COPS5 affects COPS2
2 22 4 | 1 2
COPS5 binds COPS2.
2 22 4 | 2
22 2 |

No evidence text available

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COPS5 binds COPS2 bound to GPS1, COPS6, COPS5, COPS8, COPS4, COPS7A, and COPS3. 1 / 1
1 |

"The COP9 signalosome (CSN) is a multiprotein complex that plays a critical role in diverse cellular and developmental processes in various eukaryotic organisms. we have performed a comprehensive proteomic analysis of the human CSN complex using a new purification method and quantitative mass spectrometry. Purification of the human CSN complex from a stable 293 cell line expressing N-terminal HBTH-tagged CSN5 subunit was achieved by high-affinity streptavidin binding with TEV cleavage elution."
| 1

sparser
"Among these proteins, JAB1, COPS2, COPS3, COPS4 and COPS7A are members of the CSN complex; xref therefore, interactions of pJAB1 with COPS2, COPS3 and COPS4 are easy to understand and may be involved in multiple functions of the CSN complex."
1 |

No evidence text available
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No evidence text available

sparser
"In mammals, single CSN2 and CSN5 subunits interact with nuclear receptors to function as a co-repressor and a co-activator, respectively, in steroid hormone signaling xref – xref ."
COPS5 binds COPS2 bound to GPS1, COPS6, COPS5, COPS8, COPS4, COPS7B, and COPS3. 1 / 1
1 |

"The COP9 signalosome (CSN) is a multiprotein complex that plays a critical role in diverse cellular and developmental processes in various eukaryotic organisms. we have performed a comprehensive proteomic analysis of the human CSN complex using a new purification method and quantitative mass spectrometry. Purification of the human CSN complex from a stable 293 cell line expressing N-terminal HBTH-tagged CSN5 subunit was achieved by high-affinity streptavidin binding with TEV cleavage elution."
COPS5 inhibits COPS2.
| 1
COPS5 inhibits COPS2. 1 / 1
| 1

reach
"Given that knockdown of COPS2, but not COPS5 or COPS8, leads to G2/M arrest of ESCs, we believed that the cycle regulatory function of COPS2 is independent of the CSN."
COPS2 affects COPS3, COPS4, COPS5, COPS6, COPS7A, COPS8, and GPS1
1 2 |

"Inferred from SIGNOR complex SIGNOR-C489"

No evidence text available

No evidence text available
GPS1 affects COPS5
2 |
1 |

No evidence text available
1 |

No evidence text available
COPS5 affects COPS3
1 | 1
| 1

sparser
"Among these proteins, JAB1, COPS2, COPS3, COPS4 and COPS7A are members of the CSN complex; xref therefore, interactions of pJAB1 with COPS2, COPS3 and COPS4 are easy to understand and may be involved in multiple functions of the CSN complex."
1 |

No evidence text available
COPS2 affects GPS1
2 |
1 |

No evidence text available
1 |

No evidence text available
COPS2 affects COPS3
1 | 1
| 1

sparser
"Among these proteins, JAB1, COPS2, COPS3, COPS4 and COPS7A are members of the CSN complex; xref therefore, interactions of pJAB1 with COPS2, COPS3 and COPS4 are easy to understand and may be involved in multiple functions of the CSN complex."
1 |

No evidence text available
| 1

sparser
"In mammals, single CSN2 and CSN5 subunits interact with nuclear receptors to function as a co-repressor and a co-activator, respectively, in steroid hormone signaling xref – xref ."
GPS1 affects GFER
1 |
1 |

No evidence text available
GPS1 affects COPS3
1 |
1 |

No evidence text available
GFER affects GPS1
1 |
1 |

No evidence text available
| 1

sparser
"In mammals, single CSN2 and CSN5 subunits interact with nuclear receptors to function as a co-repressor and a co-activator, respectively, in steroid hormone signaling xref – xref ."
COPS8 affects GPS1
1 |
1 |

No evidence text available
| 1

sparser
"In mammals, single CSN2 and CSN5 subunits interact with nuclear receptors to function as a co-repressor and a co-activator, respectively, in steroid hormone signaling xref – xref ."
COPS5 affects GFER
1 |
1 |

No evidence text available
COPS5 affects CSN2
| 1

sparser
"In mammals, single CSN2 and CSN5 subunits interact with nuclear receptors to function as a co-repressor and a co-activator, respectively, in steroid hormone signaling xref – xref ."
COPS5 affects COPS8
1 |
1 |

No evidence text available
COPS5 affects COPS4
| 1
| 1

sparser
"Among these proteins, JAB1, COPS2, COPS3, COPS4 and COPS7A are members of the CSN complex; xref therefore, interactions of pJAB1 with COPS2, COPS3 and COPS4 are easy to understand and may be involved in multiple functions of the CSN complex."
COPS3 affects GPS1
1 |
1 |

No evidence text available
COPS3 affects COPS4
| 1
| 1

sparser
"Among these proteins, JAB1, COPS2, COPS3, COPS4 and COPS7A are members of the CSN complex; xref therefore, interactions of pJAB1 with COPS2, COPS3 and COPS4 are easy to understand and may be involved in multiple functions of the CSN complex."
| 1

sparser
"In mammals, single CSN2 and CSN5 subunits interact with nuclear receptors to function as a co-repressor and a co-activator, respectively, in steroid hormone signaling xref – xref ."
COPS2 affects GFER
1 |
1 |

No evidence text available
COPS2 affects CSN2
| 1

sparser
"In mammals, single CSN2 and CSN5 subunits interact with nuclear receptors to function as a co-repressor and a co-activator, respectively, in steroid hormone signaling xref – xref ."
COPS2 affects COPS8
1 |
1 |

No evidence text available
| 1

sparser
"In mammals, single CSN2 and CSN5 subunits interact with nuclear receptors to function as a co-repressor and a co-activator, respectively, in steroid hormone signaling xref – xref ."
COPS2 affects COPS5, COPS8, GFER, and GPS1
1 |
1 |

No evidence text available
COPS2 affects COPS4
| 1
| 1

sparser
"Among these proteins, JAB1, COPS2, COPS3, COPS4 and COPS7A are members of the CSN complex; xref therefore, interactions of pJAB1 with COPS2, COPS3 and COPS4 are easy to understand and may be involved in multiple functions of the CSN complex."
COPS2 affects COPS3, COPS5, and GPS1
1 |
1 |

No evidence text available
COPS2 affects COPS3, COPS4, COPS5, COPS6, COPS7B, COPS8, and GPS1
1 |

"Inferred from SIGNOR complex SIGNOR-C487"
1 |

No evidence text available
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No evidence text available

No evidence text available

No evidence text available
COPS2 affects COPS3, COPS4, and COPS5
| 1
| 1

sparser
"Among these proteins, JAB1, COPS2, COPS3, COPS4 and COPS7A are members of the CSN complex; xref therefore, interactions of pJAB1 with COPS2, COPS3 and COPS4 are easy to understand and may be involved in multiple functions of the CSN complex."