A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

IndraLab

Statements

databases
phosphosite cbn pc11 biopax bel_lc signor biogrid tas lincs_drug hprd trrust | geneways tees isi trips rlimsp medscan sparser reach
reading

CEBPB affects SMAD3, and YY1
| 8
YY1 binds CEBPB and SMAD3. 7 / 7
| 7
sparser
"To further clarify the interaction between specific transcription factors, such as C/EBPβ, YY1 and Smad3, in the mouse Amtn gene promoter in vivo , chromatin immunoprecipitation assays (ChIP) assays were carried out."
sparser
"Hence, we proposed that Pg LPS increased Smad3 binding to C/EBPβ and YY1, and thereby upregulated Amtn gene transcription."
sparser
"Considering to the results of C/EBPβ, YY1, Smad3 and pSmad3 protein levels after stimulation by Pg LPS (Fig.  xref and Table 3), LPS‐induced C/EBPβ, YY1 and pSmad3 directly bind to C/EBP1, 2 and YY1 elements, respectively, mediating their physical interaction with Smad3."
sparser
"Furthermore, we identifiedLPS‐modulated interactions with C/EBPβ,YY1 and Smad3."
sparser
"Here, we report that Pg LPS‐induced physical interactions between C/EBPβ, YY1 and Smad3 upregulate Amtn gene transcription via mitogen‐activated protein kinase kinase 1/2 (MEK1/2), phosphatidylinositol 3‐kinase (PI3‐K) and Smad2/3 pathways in mouse gingival epithelial cells."
sparser
"C/EBPβ and YY1 directly interact with Smad3 in GE1 cells."
sparser
"In this study we have shown that Pg LPS induced Amtn gene transcription that was mediated through C/EBPβ, YY1 and Smad3 binding to C/EBP1, C/EBP2 and YY1 elements, which was accompanied by physical interaction between C/EBPβ, YY1 and Smad3."
YY1 binds CEBPB, SMAD3, and SMAD3. 1 / 1
| 1
sparser
"We next investigated effects of Pg LPS on the protein levels of transcription factors, such as C/EBPβ, YY1, Smad3 and pSmad3 which bind to C/EBP1, C/EBP2 and YY1 elements in the mouse Amtn gene promotor."
CEBP affects CEBPB, SMAD3, and YY1
| 1
CEBP binds YY1, CEBPB, and SMAD3. 1 / 1
| 1
sparser
"These results demonstrate that Pg LPS regulates Amtn gene transcription via binding of C/EBPβ-Smad3 and YY1-Smad3 complexes to C/EBP1, C/EBP2 and YY1 response elements in the mouse Amtn gene promoter."