IndraLab

Statements

TIAM1 bound to SMO is active. 2 / 2
2 |
signor
"This latter work suggested that inactive smo prevents rac1 activation by interacting with the rac guanine nucleotide exchange factor (gef) t-lymphoma invasion and metastasis 1 (tiam1). This smo-tiam1 complex dissociates upon shh-mediated activation of smo, thus allowing tiam1 to activate rac1"
20654717
signor
"This latter work suggested that inactive smo prevents rac1 activation by interacting with the rac guanine nucleotide exchange factor (gef) t-lymphoma invasion and metastasis 1 (tiam1). This smo-tiam1 complex dissociates upon shh-mediated activation of smo, thus allowing tiam1 to activate rac1"
23074268
Phosphorylated TIAM1 is active. 1 / 1
1 |
signor
"Tiam1 cooperated with src to induce activation of rac1 in vivo and the formation of membrane ruffles."
12810717
Threonine-phosphorylated TIAM1 is active. 1 / 1
1 |
biopax:pid
No evidence text available
9407095