IndraLab

Statements


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"After adjusting for confounders, HCQ was protective of renal damage occurrence in full (hazard ratio [HR] 0.12, 95% confidence interval [95% CI] 0.02 -- 0.97, p = 0.0464) and reduced (HR 0.29, 95% CI 0.13 -- 0.68, p = 0.0043) models."

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"Moreover, our study found that HCQ reduced the incidence of preeclampsia (weighted HR 0.51)."

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"Conversely, HCQ use with SGLT2i abolished this protective effect (HR 1.57, 95% CI 0.99–2.51 and HR 1.54, 95% CI 0.86–2.76 in ITT and AT analysis, respectively)."

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"Cumulative glucocorticoid use raised the mortality rate, whereas the HR was reduced by 45% with cumulative low-dose HCQ use."

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"After adjusting for confounders, hydroxychloroquine was protective of renal damage occurrence in full (HR = 0.12; 95% CI 0.02-0.97; p = 0.0464) and reduced (HR = 0.29; 95% CI 0.13-0.68; p = 0.0043) models."

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"Hydroxychloroquine use reduced the risk of death (HR = 0.46, 95% CI 0.29 to 0.72, p < 0.05) and renal damage (HR = 0.30, 95% CI 0.13 to 0.68, p < 0.05)."

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"Long-term HCQ therapy may decrease the HR of CAD in SS patients."

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"Male sex (hazard ratio [HR] 2.42, p < 0.01), end-stage renal disease (ESRD; HR 1.74, p = 0.01), recent use of mycofenolate mofetil (MMF; HR 4.43, P < 0.001), intravenous steroid pulse therapy (HR 108.73, p < 0.001), and average oral dose of> 7.5 mg/day prednisolone or equivalent (HR 4.83, p < 0.001) were associated with PJP in SLE, whereas hydroxychloroquine use reduced its risk (HR 0.51, p = 0.01)."

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"Patients who both used hydroxychloroquine and statins had reduced risk of mortality (HR 0.38), which was similar to high-dose statin users (HR 0.44)."

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"HCQ reduced the risk of infection (HR 0.73)."

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"Hydroxychloroquine prevented total (HR: 0.37; 0.26 to 0.53) and severe flares (HR: 0.33; 0.21 to 0.52), while mycophenolate and azathioprine reduced overall flares."