IndraLab

Statements



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"They demonstrated that CD4 + T cells from RA patients treated with hydroxychloroquine (HCQ) showed increased levels of LC3-II and autophagosomes number compared with cells isolated from healthy donors."

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"XREF_BIBR In contrast, another study of HIV patients who were on HAART but were nonresponders (suboptimal CD4 T-cell increases on therapy) showed that HCQ significantly increased the percentage of CD4 T-cells, which was retained 2 months after HCQ was stopped."

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"According to the report, rapamycin treatment combined with hydroxychloroquine (HCQ) reduces M2-like polarized macrophages in vitro and augments both M1/M2 and CD8/CD4 ratio in the GL261 model."