IndraLab

Statements

Dicoumarol inhibits FURIN. 3 / 3
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"An extensive drug discovery campaign identified dicoumarol compounds that inhibit the activity of furin ( Komiyama et al., 2009 )."
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"Therefore, we tested whether TLR7 processing in PMA treated THP-TLR7 cells was affected by DC1, a dicoumarol derivative that potently inhibits furin, PACE4, PC5/6, and (to a lesser extent) PC7 (Komiya[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Furthermore, furin-inhibiting dicoumarol derivatives could be identified by HTS."
| PMC