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Hydroxychloroquine activates BCL2. 2 / 2

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"CQ and HCQ can activate caspase-3 and modulate the Bcl-2 and Bax ratio inducing apoptosis in CLL, B-cell CLL and glioblastoma cells [XREF_BIBR, XREF_BIBR, XREF_BIBR - XREF_BIBR]."

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"Similarly, hydroxychloroquine treatment was reported to increase LMP induction and CB release, which was responsible for apoptotic cell death in pcDNA3.1, human Bcl2 vector transfected HeLa, and BJAB cells."

28487766

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Hydroxychloroquine activates BCL2. 2 / 2

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