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Hydroxychloroquine decreases the amount of toll-like receptors. 2 / 2
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"It has been shown that the antimalarial drug hydroxychloroquine (Plaquenil) inhibits the expression of toll-like receptors (TLRs) and the production of IL-6, and hence may have an anti-COVID-19 impact (Wang et al., 2020)."

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"Interestingly, hydroxychloroquine (Plaquenil), an antimalarial drug, has also been reported to downregulate the expression of toll like receptors (TLRs) and IL-6 production, and therefore may have potential anti-COVID-19 activity [supplementary materials 3]."