IndraLab

Statements



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"HCQ treatment can reduce low-density lipoprotein and Triglyceride serum values, and plays an anti-platelet aggregation role, thus it is considered to be cardioprotective (57)."

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"HCQ has been reported to lower the mean serum total-c, LDL-c, and triglyceride concentrations [[1], [2], [3],18]."

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"The results showed that CQ or HCQ can decrease the TC, TG, LDL-C, VLDL-C in SLE patients, and our findings are of clinical significance to some extent."

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"For example, Hydroxychloroquine (HCQ), a DMARD used in the management of RA and SLE, has been reported to produce a less atherogenic lipid profile by lowering TC, LDL and TG and increasing HDL levels [XREF_BIBR, XREF_BIBR]."

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"Treatment with CQ and HCQ at the dose between 250-400 mg decreased TC, TG, LDL-C, apolipoprotein B (apoB) and the ratio of apoB to apolipoprotein A-1 (apoA-1) but did not affect non-esterified fatty acids (NEFA) and HDL-C levels in T2DM patients 37,39."

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"Overall, we quantitatively summarize all the available evidences and find that HCQ or CQ therapy could significantly decrease the serum TC, TG, LDL-C, VLDL-C by 21.40 mg/dL, 29.07 mg/dL, 16.25 mg/dL, 6.41 mg/dL, respectively, but not HDL-C in comparison of control group."

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"Many clinical studies have found that HCQ can significantly reduce TG [3,10] and TC [10-13]."