IndraLab

Statements

eidos
"Whereas , hydroxychloroquine was first used to prevent and treat malaria and is currently used to treat rheumatoid arthritis , some symptoms of systemic lupus erythematosus , juvenile idiopathic arthritis , and other autoimmune diseases ."
32330521
eidos
"Current status of clinical trial studies on the interventions against COVID-19 across the world as of July 31 , 2020 ( Source : National Institute of Health , https://clinicaltrials.gov/ ) Accessed on Aug 1 , 2020 Hydroxychloroquine is FDA-approved to prevent and treat malaria , as well as to treat the autoimmune diseases rheumatoid arthritis and lupus [ 44-48 ] ."
| PMC
reach
"This was hydroxychloroquine, used to treat the symptoms of SLE and rheumatoid arthritis (RA) and to prevent and treat malaria, that reduced cellularity to 4.64 × 10 cells/mL in average (p = 0.0002), and FTY720, used to treat relapsing forms of multiple sclerosis, that reduced cellularity to 2.43 × 10 cells/mL in average (p < 0.0001)."
34744730
eidos
"HCQ has been extensively used to prevent malaria and as treatment for autoimmune diseases such as rheumatoid arthritis and systemic lupus erythematosus ( Olsen et al ., 2013 ) ."
31556748
eidos
"Both chloroquine and hydroxychloroquine are used to prevent and treat malaria , being some of the antimalarial drugs of choice in areas where the disease is not resistant to them ( a recurrent problem in this disease ) ; they were preferred over quinine because of much less severe adverse effects , although at present there are many other even safer alternative drugs for the treatment of malaria ."
32983220
reach
"There should be close monitoring for adverse drug reactions and discontinuation of the drug if intolerable adverse reaction develops (http://www.gov.cn/zhengce/zhengceku/2020-03/04/5486705/files/ae61004f-930d47598711a0d4cbf874a9.pdf)Hydroxychloroquine has been used for decades to prevent and treat malaria (it was first used during World War II) and is also effective as an anti-inflammatory and immunomodulatory agent for the management of various autoimmune rheumatic diseases, such as rheumatoid arthritis, Sjögren’s syndrome, systemic lupus erythematosus, and even sarcoidosis."
32411941
reach
"Hydroxychloroquine is used to prevent and treat malaria in areas where malaria remains sensitive to chloroquine."
34130375
eidos
"Both CQ and HCQ are used to prevent and treat malaria in endemic areas of the world ."
32848158
reach
"Whereas, hydroxychloroquine was first used to prevent and treat malaria and is currently used to treat rheumatoid arthritis, some symptoms of systemic lupus erythematosus, juvenile idiopathic arthritis, and other autoimmune diseases.Although ongoing clinical trials are testing the efficacy and safety of several treatments for COVID-19, including chloroquine and hydroxychloroquine, there is not yet credible evidence from clinical trials on the efficacy and safety of those agents in COVID-19."
32330521
ctd
No evidence text available
18061791
ctd
No evidence text available
17202178
eidos
"Antimalarials Chloroquine and hydroxychloroquine have been used since the 1930s to prevent and treat malaria and to treat chronic inflammatory diseases , including rheumatoid arthritis and systemic lupus erythematosus ( 90 ) ."
33195600
reach
"However, another retrospective study demonstrated little effect of umifenovir on improving clinical consequences in non-ICU patients [201] , suggesting more trials for accessing the effects of umifenovir in COVID-19.Chloroquine (CQ) and hydroxychloroquine (HCQ) are used to prevent/treat malaria."
34204163