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Alantolactone inhibits CTSB. 2 / 2
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"The application of alantolactone can enhance autophagosomes through disrupting autophagic degradation and suppressing activity of CTSB/CTSD proteins to accelerate apoptosis and enhance drug sensitivit[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Moreover, He et al. detected that alantolactone caused the accumulation of autophagosomes due to impaired autophagic degradation and substantially inhibited the activity and expression of CTSB/CTSD (cathepsin B/ cathepsin D) proteins when depleted, causing lysosomal dysfunction [103]."
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