IndraLab

Statements

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"Salicylates, indomethacin, phenylbutazone and hydroxychloroquine produce some clinical improvement but do not lower the high ESR; moreover, the patients are prone to experience relapses."
1249388
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"The combining results of these three studies showed that when compared with placebo group, HCQ treatment could effectively reduce ESR in patients with pSS."
28499370
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"Therefore, it was concluded that HCQ had no effect upon pain, fatigue, but HCQ could reduce the ESR of pSS patients.With regard to the safety of HCQ in the treatment of SS, three [31, 37, 39] of the four studies recorded side effects or adverse events after treatment."
28499370
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"These results were not completely consistent with previous related studies, which have shown that HCQ can improve patient 's fatigue and joint symptoms, and effectively reduce immunoglobulin, ESR, and CRP levels [XREF_BIBR, XREF_BIBR]."
28769984
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"For the objective indexes, as salivary flow rate was only measured in one study which could not be used for meta-analysis, so only the pooled weighted mean difference of the ESR and Schirmer test were analyzed (Table 5), and it was found that HCQ treatment could reduce the ESR of SS patients (Z = −2.19, P < 0.05; Fig. 10), however, there was no statistically significant difference in Schirmer test (Z = 0.04, P = 0.97; Fig. 11)."
28499370
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"Previous research studies have shown that HCQ or TGP can reduce ESR; thus, IGU might enhance the anti-inflammatory activity of HCQ or TGP through a synergistic effect or independent pathways."
33815105
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"And HCQ treatment could also reduce the ESR of pSS patients,however, when considering the treatment result of Schirmer test, no significant difference between HCQ and control groups was found."
28499370