IndraLab

Statements



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"HCQ can reduce gastrointestinal absorption of methotrexate, since it alters the local pH and it can explain lower toxicity of methotrexate when combined."

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"HCQ and methotrexate, when administered together, may reduce the absorption of methotrexate through a change in pH [55]."

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"A combination of hydroxychloroquine with methotrexate appears to reduce significantly the hepatic toxicity of methotrexate."

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"Hydroxychloroquine does not decrease serum methotrexate concentrations in children with juvenile idiopathic arthritis."

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"HCQ can reduce gastrointestinal absorption of methotrexate, since it alters the local pH and it can explain lower toxicity of methotrexate when combined."