IndraLab

Statements

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"Autophagy can also be blocked at the level of the lysosome with drugs such as hydroxychloroquine which inhibits lysosomal acidification.In PDA, autophagy levels are basally high even when grown in com[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Hydroxychloroquine (HCQ), a well tolerated inhibitor of autophagy, reduces growth of PDA in GEMMs and human xenografts [XREF_BIBR, XREF_BIBR] and is now under evaluation in clinical trials for PDA and other malignancies."
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