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"We recently reported that 1) phenytoin suppressed cathepsin-L activity at transcriptional level in gingival fibroblasts in vitro (Yamada et al., 2000), and that 2) the mice deficient in cathepsin-L ge[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"Nifedipine, cyclosporine and phenytoin selectively inhibited cathepsin-L activity (but not that of cathepsin-B) and mRNA expression in cultured gingival fibroblasts [92,93]."

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"An in vitro study showed that phenytoin and cyclosporine can inhibit the production of cathepsin L, but not B, by gingival fibroblasts [XREF_BIBR] and transgenic mice deficient for cathepsin L spontaneously develop GO [XREF_BIBR]."