
IndraLab
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Amodiaquine inhibits enzyme activity. 1 / 1
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"PkPMTs enzyme activity could be inhibited by amodiaquine, chloroquine, and NCI compound NSC158011, whereas the yeasts carrying mutant PkPMT genes are unable to carry out phosphatidylcholine biosynthesis from phosphoethanolamine. xref Disruption of phosphatidylcholine synthesis in Plasmodium would lead to failure of intact Plasmodium membrane formation and thus inhibit parasite proliferation."