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Hydroxychloroquine increases the amount of CXCL10. 3 / 3
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"Interestingly, 535 hydroxychloroquine was reported to increase expression of CXCL10 and IFIT3 in human lung 536 carcinoma cells and mouse macrophages (Wang et al., 2015), the opposite of the desired effect 537 proposed from our computational findings."
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"We also identified that HCQ could decrease lesion numbers and disrupt lesion histopathology, as well as increase the levels of peritoneal macrophages and the IP-10 (10kDa interferon-gamma-induced protein) chemokine in a mouse model of endometriosis."