IndraLab
Statements
Hydroxychloroquine inhibits NADPH. 1 / 1
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"Two potential pathways were inferred to be involved in the protective effect of hydroxychloroquine in CAD : (a) hydroxychloroquine may activate ERK5 (encoded by MAPK7) to prevent endothelial inflammation via inhibition of cell adhesion molecule expression 24; and (b) hydroxychloroquine may inhibit endosomal activation of NADPH oxidase in response to pro inflammatory agonists (TNF-alpha and IL-1beta) and may decrease production of pro inflammatory cytokines in stimulated immune cells 25."