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"The analogous carbamate compounds 1q and 1p (XREF_FIG), containing guanidino groups at the meta- and para-positions of the phenyl ring respectively, displayed micromolar potency against furin in vitro, but were moderately cytotoxic (1q, 1p) and, except for 1p, did not inhibit intracellular furin even at a concentration of 100 microM (XREF_FIG)."