IndraLab

Statements



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"Hydroxychloroquine has been shown to induce MG on its own, as has pembrolizumab [7,14]."

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"While we do not believe that the patient’s MG was triggered by hydroxychloroquine alone, as she had been taking this for the long term, it could be that an interaction between the immunomodulatory effects of both hydroxychloroquine and pembrolizumab occurs."

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"Indeed, hydroxychloroquine may worsen the clinical manifestations of MG or induce MG itself."

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"44 A review analysed the association between these two diseases and offered the possibility that hydroxychloroquine, a drug typically used for the treatment of SLE, could have induced MG, at least in one patient."

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"Among eight patients (47%) who developed MG after initiation of hydroxychloroquine, the question of induction of MG by hydroxychloroquine was raised in one patient."

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"Notably, hydroxychloroquine, especially in combination with azithromycin, can cause new onset or aggravation of MG."

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"In the era of the COVID-19 pandemic, when HCQ has been widely used as prophylactic treatment, Elavarsi and Goyal [6] reported the exacerbation of myasthenic symptoms in a young AChR-positive myasthenic lady treated with HCQ and emphasized the need for awareness of the possibility of HCQ-induced MG."