IndraLab

Statements

1,2-bis(diphenylphosphino)ethane inhibits CTSB. 6 / 6
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"Since we have shown here that DPPE 1.2 inhibits parasite cathepsin B, killing of L. (L.) amazonensis in infected mice treated with the drug may be associated to protective responses arising from lower expression of the active form of TGF-beta."
22616018
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"DPPE 1.1 Inhibits the Cathepsin B Activity of L. (L.) amazonensis Amastigotes."
30018604
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"The cathepsin B activity of L. (L.) amazonensis amastigotes was inhibited by DPPE 1.1 as demonstrated spectrofluorometrically by use of a specific fluorogenic substrate."
30018604
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"We showed that DPPE 1.1 inhibited the high cathepsin B activity expressed in L. (L.) amazonensis amastigotes."
30018604
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"The calculated IC50 values for DPPE 1.2 and CA074 were not significantly different (2.25±0.11 µM and 0.7±0.08 µM, respectively), strongly suggesting that DPPE 1.2 inhibits L. (L.) amazonensis cathepsin B."
22616018
sparser
"Since we have shown here that DPPE 1.2 inhibits parasite cathepsin B, killing of L. (L.) amazonensis in infected mice treated with the drug may be associated to protective responses arising from lower expression of the active form of TGF-β."
22616018