IndraLab

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"CQ and HCQ can activate caspase-3 and modulate the Bcl-2 and Bax ratio inducing apoptosis in CLL, B-cell CLL and glioblastoma cells [XREF_BIBR, XREF_BIBR, XREF_BIBR - XREF_BIBR]."

No evidence text available

reach
"In contrast to wild-type p53 AML (TP53 wt), HCQ treatment did not trigger a BAX and PUMA dependent apoptotic response in AMLs harboring TP53 mut."