IndraLab

Statements

Hydroxychloroquine activates Neoplasm Invasiveness. 5 / 5
| 5
reach
"26 , 27 Some of these in vitro studies demonstrated that HCQ can partially enhance the invasion function of trophoblasts and affect the release of inflammatory factors."
35770338
reach
"In a mouse model of obstetric antiphospholipid syndrome, Liu et al. observed that HCQ treatment could partially reverse the process of aPL antibodies reducing trophoblastic invasion and migration, This improvement in placental function helps prevent fetal death and reduces the incidence of pathological pregnancies [52]."
38711668
reach
"44 In the present study, TLRs inhibitor HCQ reversed the function of SESN1 siRNA in NB cell proliferation, cell migration, and cell invasion, which may be via a MyD88‐dependent pathway.NB is a typical “cold tumor” with an impressive immune microenvironment, and immune microenvironment has been reported to regulate the metastasis of several tumors, including NB."
38516781
reach
"The transwell invasion assay shows that PHCQ NP and HCQ at a non-toxic concentration caused a ∼35% decrease of cell invasion, while PSN38 NP reduced cell invasion by ∼40% ( Fig. 3 D–E)."
35286855
reach
"Hydroxychloroquine could also antagonize aPL-mediated inhibition of trophoblast migration, invasion and differentiation [13,14] ."
25617818