IndraLab
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"According to a study, cathepsin B and K are effectively inhibited by the Ag in silver diamine fluoride (SDF), which may prevent the advancement of caries by either blocking the active site of collagen to protect it from enzymatic attack or by inactivating enzyme-mediated collagen degradation (66)."
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"Cathepsin B like activity was totally inhibited by the specific inhibitor lepeptin (0.1 mM); while DPP-II-like activity was partially inhibited by Tris (10 mM) or puromycin (0.1 mM), which are specific for DPP II, and by phenylmethylsulphonyl fluoride (PMS-F), an inhibitor of serine class proteases."